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Pragmatic trials are studies designed to provide information for the real-world practice of clinical. They are typically characterized by a focus on practical aspects of the research design, like the recruitment and consent process as well as adherence to the use of commonly available equipment.
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Pragmatic, a software company offers a range of casino games to online gambling platforms. Pragmatic's iGaming software is used by the top operators and land based casinos. The company offers front-end design tools, analysis, marketing, promotions payment systems, security, customer service and bug reporting. Additionally, the company provides its users a safe environment with high-quality graphics as well as gameplay.
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RTP
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Another example of a trial that is pragmatic is the Home Blood Pressure Management (HBPM) study, which used various investigators and participants from different geographical regions. This type of heterogeneity is required for practical trials to be valid and helps reduce the chance of bias in the results. However excessive heterogeneity could lead to problems with the design of the trial.
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Mobile compatibility
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Legality
Pragmatic Play has earned a name for itself by providing high-quality games and a superior user experience. Its software can be used on mobile devices as well as in various languages. It has earned itself the status of one of the leading gaming platforms in the casino industry despite its relatively young age. Wolves is one of the most recent releases, a 5-reel slot machine with a healthy RTP and impressive graphics. Other notable games include Wolf Gold and Chilli Heat.
The aim of pragmatic trials is to simulate real-life scenarios and to achieve the highest level of validity externally. They are usually requested by practitioners and policy makers to guide their decision-making. They can also be a great method to determine the causality between the intervention and its effects. However, they shouldn't be used in lieu for explanation studies.
The pragmatism idea is controversial and there are doubts about whether pragmatic trials should be used to replace explanatory trials or complement them. Schwartz and Lellouch1 suggested a distinction between explanatory trials, which validate a physiological or clinical hypothesis as well as pragmatic trials that inform the practice and policy decisions. They also proposed a framework called PRECIS for pragmatic trials.2 The tool was designed to define the traits of a practical study which includes the recruitment, design, and delivery of the intervention and its follow-up.
The number of pragmatic trials is growing. A recent Medline query that used the words pragmatic and naturalistic, limited to randomised controlled trials (RCTs), returned 34 articles. They are displayed in red on Figure 2. This suggests that the health sciences community has become more aware of the importance of pragmatic thinking. It is important to remember that the majority were conducted in primary-care settings.